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About:
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2 opiate agonist medicines, methadone as well as LAAM (levo-alpha-acetylmethadol), have been accepted for the therapy of opiate dependency. Agonists act by replacing at the opioid receptor website, consequently blocking the ecstasy of consequently administered narcotics (using crosstolerance) and preventing the signs and symptoms of intense as well as persistent abstinence. Methadone was authorized for use in 1972, and there are presently an estimated 650 methadone maintenance programs throughout the United States (IOM, 1995a, b). In 1993, LAAM was approved for use in treating opiate reliance; this drug has the advantage of calling for three doses weekly rather than everyday dosages, therefore releasing subjects from everyday facility attendance.
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